You can use a simple wrapper around htlatex if you don't mind the issues I described in my previous post. This version is for Unix based OSes:

#!/bin/bash
htlatex "$@"
base=${1%.tex}
rm $base.dvi
rm $base.idv
rm $base.lg
rm $base.tmp
# following files should be kept IMHO
# the log file can be usefull for error investigation
rm $base.log
# these files are reused between TeX runs, it is not a good idea to delete them
rm $base.4tc
rm $base.4ct
rm $base.aux
rm $base.xref

I would say that deleting the dvi, idv, lg and tmp files should be quite safe, as they are generated every time from the scratch and the subsequent compilations don't depend on them.

Hi Hilmar, as Karl and Nasser said, there is no cleanup performed by htlatex or other tex4ht scripts by default. The auxilary files are in fact quite important for the correct conversion, so it is not a good idea to delete them after every compilation. For example some complex tables may need more than three compilations by LaTeX to correctly resolve the structure, so you would never get a correct result with removed aux files.

https://bugs.debian.org/554637

I've noticed that running

htlatex test.tex "xhtml,ooffice,enumerate+" "ooffice/! -cunihtf -utf8" "-coo"

pollutes current directory with the following intermediate files:

test.4ct
test.4tc
test.dvi
test.idv
test.tmp
test.xref

As htlatex is actually trying to do some cleanup, I think these should be removed as well. I only expect the following files to stay:

test.lg
test.odt

Test input file:
\documentclass{article}
\begin{document}
test
\end{document}